Arabidopsis Synaptotagmin 1 Is Required for the Maintenance of Plasma Membrane Integrity and Cell Viability
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چکیده
منابع مشابه
Arabidopsis synaptotagmin 1 is required for the maintenance of plasma membrane integrity and cell viability.
Plasma membrane repair in animal cells uses synaptotagmin 7, a Ca(2+)-activated membrane fusion protein that mediates delivery of intracellular membranes to wound sites by a mechanism resembling neuronal Ca(2+)-regulated exocytosis. Here, we show that loss of function of the homologous Arabidopsis thaliana Synaptotagmin 1 protein (SYT1) reduces the viability of cells as a consequence of a decre...
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In eukaryotes, vesicle trafficking is regulated by the small monomeric GTPases of the Rab protein family. Rab11, (a subfamily of the Ypt/Rab gene family) an evolutionarily conserved, ubiquitously expressed subfamily of small monomeric Rab GTPases, has been implicated in regulating vesicular trafficking through the recycling of endosomal compartment. In an earlier communication, we have shown th...
متن کاملTriggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering.
The extended synaptotagmins (E-Syts) are ER proteins that act as Ca(2+)-regulated tethers between the ER and the plasma membrane (PM) and have a putative role in lipid transport between the two membranes. Ca(2+) regulation of their tethering function, as well as the interplay of their different domains in such function, remains poorly understood. By exposing semi-intact cells to buffers of vari...
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As you will see, while the referees consider that your study deepens our knowledge on the regulation of E-Syt1, they also raise several concerns and think that some of your conclusions are not sufficiently supported by the data provided. I won't list all concerns here, as all reports are very constructive and clear. Essentially, more insight and controls regarding the calcium-mediated regulatio...
متن کاملrab11 is required for maintenance of cell shape via βps integrin mediated cell adhesion in drosophila
in eukaryotes, vesicle trafficking is regulated by the small monomeric gtpases of the rab protein family. rab11, (a subfamily of the ypt/rab gene family) an evolutionarily conserved, ubiquitously expressed subfamily of small monomeric rab gtpases, has been implicated in regulating vesicular trafficking through the recycling of endosomal compartment. in an earlier communication, we have shown th...
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ژورنال
عنوان ژورنال: The Plant Cell
سال: 2008
ISSN: 1532-298X
DOI: 10.1105/tpc.108.063859